![]() ![]() The primary aim of the MHC Haplotype Project was to provide a comprehensively annotated reference sequence of a single, human leukocyte antigen-homozygous MHC haplotype and to use it as a basis against which variations could be assessed from seven other similarly homozygous cell lines, representative of the most common MHC haplotypes in the European population. ![]() The human major histocompatibility complex (MHC) is contained within about 4Â Mb on the short arm of chromosome 6 and is recognised as the most variable region in the human genome. Trevanion, Steve Wilming, Laurens Rogers, Jane de Jong, Pieter J. Hart, Elizabeth Howe, Kevin Jackson, David K. Almeida, Jeff Forbes, Simon Gilbert, James G. Horton, Roger Gibson, Richard Coggill, Penny Miretti, Marcos Allcock, Richard J. Variation analysis and gene annotation of eight MHC haplotypes: The MHC Haplotype Project ![]()
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